Association of Rotavirus-Infected Children with Expression Levels of IFN-Gamma, TNF-α and Lipid Profile [Total Cholesterol, Triglyceride, LDL-C and HDL-C]

Authors

  • Assist. Prof. Hider M. H. Al-Shirifi Al-Qasim Green University, Faculty of Environmental Sciences, Environmental health Department, Iraq.
  • Assist. Prof. Dr. Hiba Jasim Hamza University of Babylon, College of Nursing, Medical & Basic Sciences Department, Iraq.
  • Prof. Dr. Abbas. K. Al-Mansoori AL-Qasim Green University, Faculty of Biotechnology, Department of Applied Biotechnology, Iraq.
  • Ahmed Obaid Hossain AL-Qasim Green University, Faculty of Biotechnology, Department of Medical Biotechnology, Iraq.

Keywords:

Rotavirus, Infected, Children, Lipid

Abstract

Backgrounds: Worldwide, rotavirus is a leading cause of severe gastroenteritis in children younger than five years old. Patients with impaired immune systems, such as those undergoing organ transplants (both in children and adults), are also at increased risk. The mature enterocytes at the tips of the intestinal villus are the main targets of rotavirus infection, which causes severe diarrhoea. Nevertheless, infections can spread throughout the body and affect organs outside of the digestive tract, such as the kidneys, central nervous system, liver, and lungs.

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References

Hill SL, Rose NR (2010) The transition from viral to autoimmune myocarditis. Autoimmunity 34:169–176

Leal, R.F., Planell, N., Kajekar, R., Lozano, J.J., 2015. Identification of inflammatory mediators in patients with Crohn's disease unresponsive to anti-TNFalpha therapy. Gut 64, 233–242.

Masclee, G.M., Penders, J., Pierik, M., Wolffs, P., Jonkers, D., 2013. Enteropathogenic viruses: triggers for exacerbation in IBD? A prospective cohort study using real-time quantitative polymerase chain reaction. Inflamm. Bowel Dis. 19, 124–131.

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Published

2025-03-16

How to Cite

M. H. Al-Shirifi , A. P. H., Jasim Hamza , A. P. . D. H., K. Al-Mansoori , P. D. A., & Hossain , A. O. (2025). Association of Rotavirus-Infected Children with Expression Levels of IFN-Gamma, TNF-α and Lipid Profile [Total Cholesterol, Triglyceride, LDL-C and HDL-C]. Clinical Images and Case Reports, 3(03), 01–09. Retrieved from https://www.visionpublisher.info/index.php/cicr/article/view/230

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