The Prevalence of People about to get Married who Carry Genes for Hereditary Blood Diseases and their Relationship to the Occurrence of the Disease
Keywords:
Genes, Hereditary Blood, Relationship, DiseaseAbstract
Hereditary hematologic disorders originate from genetic factors that cause disruptions of blood homeostasis. Clinics for couples planning to get married have all the data on people carrying genetic diseases, while the Center for Hereditary Blood Diseases has all the data on people affected. This study aimed to conduct an epidemiological study to obtain a comprehensive epidemiological picture regarding the percentage of people about to marry who carry hereditary diseases and the percentage of recent infections recorded in the same years studied. The current study was recorded among 58,958 couples who visited the upcoming marriage clinic during the period from 2019 to 2023, the study showed 12602 (21.37%) of people were have hereditary and non-hereditary anemia, the highest percentage of anemia patients was showed in the year 2023, 37.32%, followed in the year 2022, 20.33%, in contrast the lowest anemia patients recorded in year 2022, 14.13%. The present study was noted that the hereditary anemia was beta thalassemia 3.36%, followed alpha thalassemia 2.02%, in contrast the lowest hereditary anemia was trait 0.05%. also, showed 910 (7.22%) of people had hereditary anemia, in contrast a 11692 (92.78%) had non-hereditary anemia. This study was investigated a positive correlation between people carried beta-thalassemia anemia gene, trait thalassemia gene and sickle cell anemia gene, and the birth of children with genetic diseases, while non-significant correlation with regard alpha-thalassemia.
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