Antimicrobial Properties of Ethanolic and Other Components Chromatographic Analysis of Artemisia annua Leaf Extract and Its Functional Groups
Keywords:
Chromatographic Analysis, Antimicrobial Properties, Artemisia annua, Functional GroupsAbstract
Numerous studies have demonstrated that the essential oil and extracts of Artemisia annua has antibacterial characteristics, rendering them efficient against many bacteria and fungi. Some researchers think that the plant's ability to kill both Gram-positive and Gram-negative bacteria is due to the bioactive chemicals it contains, including as artemisinin and terpenes. Using chromatographic analysis of functional groups and ethanolic Artemisia annua leaf extract, this study intends to assess the antibacterial capabilities of the plant. The results of the GC-MS analysis proved the presence of the compounds, which are 9-Octadecenoic acid, (-)-delta-cadinene, Tetraneurin E, 1-tert-Butyl-4,4-diphenylpiperidine, Lucenin-2, Germacrene D-4-ol, 4-(2,3-Diphenylcyclopropyl)phenol, Farnesene, Tetracosahexaenoic acid, beta-Caryophyllene oxide, and Isochinol. According to (methanol, Ethyl acetate, and Ethanol fraction), Ampicillin (AMP) and Cefotaxime (CTX). Recorded (28.00±0.45, 18.00±0.28, 23.00 ±0.40, 33.01±0.51 and 30.00±0.49) respectively in Staphylococcus aureus. While recorded (22.91±0.81, 14.09±0.23, 24.00±0.41, 29.00±0.48 and 26.98±0.45) for Escherichia coli. Record (24.19±0.38, 18.09±0.27, 21.26±0.29, 31.08±0.50 and 28.16±0.49) Streptococcus pyogenes. While (21.95±0.38, 25.96±0.42, 27.00±0.44, 27.95±0.48 and 23.00±0.45) for Staphylococcus epidermidis. The metabolites of Artemisia annua exhibited significant activity against Staphylococcus aureus (28.00±0.45).
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